ESR 9 Miranda Melis


Temporal relationship between bioenergetics function and immune suppression in vitro and in vivo


Bloomsbury Institute for Intensive Care Medicine, University College London



Short CV

I finished my MSc in Molecular Nutrition and Toxicology (Wageningen University, The Netherlands), and my MSc in Policy Analysis for the Health and Life Sciences (VU University Amsterdam, The Netherlands) in 2017. By combining these MScs, I have not only learned how to perform both qualitative and quantitative research, but also acquired a unique insight into applying any findings into practical societal settings. During my MScs, I have completed various research projects and interned at highly regarded research institutes and governmental organisations both at a national and international level.

My first MSc research project was part of a large randomized controlled trial (RCT) about the effects of whole grain wheat on endothelial health and inflammation. This research was conducted at the Division of Nutrition, Metabolism and Genomics of Wageningen University under supervision of Prof. Sander Kersten. During such study, I measured leukocyte and neutrophil specific cell surface adhesion molecules in blood samples by fluorescence-activated cell sorting (FACS). For my second MSc project I moved to Melbourne, Australia, to study the effects of breastfeeding on leptin gene methylation and its genetic regulation in twins at the Murdoch Children’s Research Institute under supervision of Prof. Richard Saffery. In addition to these research projects, I have interned at the Public Health Service of Amsterdam and the Ministry of Health in the Netherlands. In this role, I worked on food fortification and healthy eating promotion for primary school children.

Because of my international experience and dual MSc programme, I was thrilled to learn about the ESA-ITN and its interdisciplinary nature. I am very grateful for the opportunity I have been given to become part of this big international collaborative project and to contribute to the development of new treatment strategies in the field of sepsis under supervision of Prof. Mervyn Singer.